Potential role of biosynthesized silver nanoparticles from Aaronsohnia factorovskyi on Hymenolepis nana in BALB/c mice

نویسندگان

چکیده

ABSTRACT Hymenolepiasis is the most common intestinal tapeworm infection in humans caused by an cestode, Hymenolepis nana. Praziquantel (PZQ) effective drug among other compounds, however, many cases of resistance have been reported. Recent research projects focused on finding novel therapeutic agents from medicinal plants. In present study, Aaronsohnia factorovskyi was used against hymenolepiasis forms plant extract (AF) and biosynthesized nanoparticles (AF-NPs) comparison to PZQ. The results showed that 100 mg/kg AF 0.5 AF-NPs were doses at suppressing fecal egg output 98.39% 100%, respectively. After 10th day treatment, it not feasible detect presence H. nana eggs sample’s examination group. Upon treatment with AF-NPs, there more improvements structure tissue than effect alone comparison, Collectively, A. factoryviski can be as anti-hymenolepiasis minimum side effects less cost. Also, found NPs are way, offers a faster recovery rate natural extract.

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ژورنال

عنوان ژورنال: Arquivo Brasileiro De Medicina Veterinaria E Zootecnia

سال: 2023

ISSN: ['1678-4162', '0102-0935']

DOI: https://doi.org/10.1590/1678-4162-13041